Evaluation of serum high sensitivity c-reactive protein (hs-crp) in vietnamese type-2 diabetic patients

 1Mui Nguyen Van, 2Nga Vu Bich, 3Quang Tran Hong

1Viet Phap Hospital, Hanoi, Vietnam

2Hanoi Medical University, Hanoi, Vietnam

3University of Public Health, Hanoi, Vietnam

ABSTRACT

High-sensitivity C-reactive protein (hs-CRP) is an acute-phase response protein that is considered both a marker of inflammation and a predictor of cardiovascular events. Studies have pointed out that type 2 diabetic individuals have higher concentrations of CRP than nondiabetic individuals, suggesting an increased role of inflammation in the acceleration of cardiovascular disease seen in these patients.

Objective

The aim of study was to know the association of hs-CRP with Diabetic and Non-diabetic individuals

Methods

A cross-sectional population-based study of 79 type 2 diabetes patients and 46 nondiabetic subjects.

Results

The mean hs-CRP concentration in diabetic group was 2.94 ± 2.14 mg/L and in normal healthy subjects was 1.68 ± 1.21 mg/L, significant difference with p< 0.001. As studying the hs-CRP distribution of the both group, we observed that 43 diabets patients (54.4 %) had the hs-CRP concentration between 1-3 mg/l and 24 patients (30.4 %) had the hs-CRP level ≥ 3 mg/l; in the nondiabetic there was 56% of the subjets had the hs-CRP level under 1mg/L; only 6.5% (3 subjets) had hs-CRP level ≥ 3 mg/l (p< 0.001)

Conclusions

Median hs-CRP levels were significantly higher in the type 2 diabetes patient compared to their nondiabetic counterparts (p<0.001). Major type 2 diabetes patient (54.4 %) had hs-CRP level between 1-3mg/L (moderate risk for cardiovascular diseases) and 30 % of type 2 diabetes patient group had hs-CRP level > 3mg/L (high risk for cardiovascular diseases).

 

Keywords: hs-CRP, types 2 diabetes patient

PHIẾU ĐẶT MUA TẠP CHÍ
THÔNG TIN QUẢNG CÁO
Bo y te
Cục KHCN & ĐT
Đại học y hà nội
Đại học Dược HN

Copyright 2012 TẠP CHÍ Y DƯỢC HỌC VIỆT NAM XUẤT BẢN BẰNG TIẾNG ANH

Giấy phép số 2477/GP-BTTTT ngày 19/12/2012.

Tổng biên tập: PGS.TS Nguyễn Thị Kim Tiến - Bộ trưởng Bộ Y tế

Văn phòng Tạp chí: P611 A1 Đại học Y Hà Nội; Số 1 - Tôn Thất Tùng - Đống Đa - Hà Nội.      

Điện thoại: (04) 3574 7782; 0915704995 (đ/c Nguyên)        Email: info@vjmp.vn        Website: vjmp.vn



THỐNG KÊ TRUY CẬP

Đang trực tuyến : 27
Tổng truy cập : 270,463